Scientific Programme

Preliminary programme and confirmed speakers

MONDAY 24th August 2020

Welcome

Diagnosis, risk factors and prognosis of TIA and minor stroke

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1. Diagnosis, significance, and management of blood pressure variability in cerebrovascular diseases
   TBC

2. Long term risks of vascular events and management after TIA and minor stroke
   TBC

3. New perspectives in imaging of transient ischaemia
   TBC

Prehospital management of acute ischemic stroke :

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1. Mobile Stroke unit : Effects on process indicators, outcomes and cost utility
   Heinrich Audebert (Berlin)

2. Debate : mother ship vs drip and ship
   TBC

   1. Utility of prehospital score to predict large artery disease

      Guillaume Turc (Paris)

   2. Place of geographic modelling of best transport option for treatment of acute ischemic stroke
      Ludwig Schlemm (London)

   3. Is there a need for randomized trials ?
      Natalia Pérez de la Ossa (Barcelone)
      Richard Macrez (Caen)

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TUESDAY 25th August 2020

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New perspectives in endovascular treatment

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1. Interventional vascular medicine with robotic assistance (Robocath)  
   Philippe Bencteux (Rouen)

2. Automated core-penumbra quantification in acute ischemic stroke : principles and different tools  
   TBC

3. Best strategies for endovascular treatment (combined devices of aspiration and stent retriever: update of evidence and current trials
   Bertrand Lapergue (Paris)

4. Mechanical thrombectomy in minor stroke and very severe stroke
   Urs Fischer (Bern)

IV thrombolytic agents

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1. Treatment with IV thrombolysis over 4.5h after stroke onset: how many patients in practice ? How could we implement this in routine ?
   Didier Leys (Lille)

2. When tenectepalse should be preferred over alteplase ?
   Daniel Strbian (Helsinki)

3. Molecular imaging of clots to predict therapeutic response
   Maxime Gauberti (Caen)

4. How to improve the thrombolytic effect of alteplase and to reduce the risk of bleeding, alteplase mutants ?
   Denis Vivien (Caen)

5. New antithrombotic targets: antiGP6, antiGP1, von Willebrand
   Sara Martinez de Lizarrondo (Caen)

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 WEDNESDAY 26th August 2020

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Genetics of stroke :

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1. How to interpret SNP, GWAS (with examples in stroke diseases)
   Stéphanie Debette (Bordeaux)

2. Omics techniques
   Martin Dichgans (Munich)

3. New approaches in gene and cellular therapies (CRISPr)
   TBC

4. Ethical issues in molecular diagnostic of inherited cerebrovascular disorders » (with examples of stroke diseases)
   Elisabeth Tournier-Lasserve (Paris)

Small vessel diseases

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1. Small vessel diseases: pathophysiology, classification, genetics
   Eric Jouvent (Paris)

2. Animal models of small vessel diseases 
   Anne Joutel (Paris)

3. Cerebral vasculitis
   TBC

4. Cerebral amyloid angiopathy
   TBC

Meeting of the executive committee on Wednesday afternoon

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THURSDAY 27th August 2020

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Heart and stroke

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1. Imaging of sporadic haemorrhagic cerebral microangiopathies
   Grégoire Boulouis (Paris)

2. Whether to resume or not antithrombotic therapies after intracerebral haemorrhage
   TBC

3. Indications and complications of left appendage closure in stroke patients with atrial fibrillation
   TBC

4. Patent foramen ovale closure in patients not included in trials: TIA patients, age > 60 years, delay from stroke > 6 months-1 year
   TBC

5. Place of implantable cardiac monitors in cryptogenic stroke ?
   TBC

Neurosurgery in stroke

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1. Hemicraniectomy for ischaemic and haemorrhagic stroke
   Bart van der Worp (Utrecht)

2. Local thrombolytic therapies in intraventricular haemorrhage: rationale, update of recent and future trials
   TBC

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FRIDAY 28th August 2020

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Workshop in the laboratory

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• Visit of a pre-clinical laboratory, animal and in vitro models of aneurysm, ischaemic stroke and haemorrhagic stroke

Statistical analyses for dummies

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• Interpretation of trials outcomes (OR, RR, HR)

• Subgroup analyses

• Meta-analyses

• Interim analyses

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